Leukotriene E4, 24-Hour Urine
Ordering Recommendation
Aids in the initial diagnosis of suspected mast cell activation disorders. A 24-hour urine collection of 300 mL or greater is required. If submitting a random urine or 24-hour collection with a total volume of less than 300 mL, refer to Leukotriene E4, Random Urine (3002351).
New York DOH Approval Status
Specimen Required
Patients taking 5-lipoxygenase inhibitor zileuton (Zyflo) may have decreased concentrations of leukotriene E4 (LTE4). If possible, discontinue 48 hours prior to collection.
24-hour urine. Refrigerate during collection.
From a well-mixed 24-hour collection transfer 5 mL urine to ARUP standard transport tubes (Min: 2 mL).
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.
Frozen. Also acceptable: Refrigerated
Collection duration and urine volume must be provided for testing. Total collection volume must be greater than 300 mL.
Ambient: 24 hours; Refrigerated: 1 week; Frozen: 28 days
Methodology
Quantitative Colorimetry/Liquid Chromatography-Tandem Mass Spectrometry
Performed
Varies
Reported
6-11 days
Reference Interval
By Report
Interpretive Data
Performed by non-ARUP Laboratory
Note
Hotline History
Hotline History
CPT Codes
82542
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3004163 | Creatinine, 24 Hour Urine | 2162-6 |
3004164 | Collection Duration: | 13362-9 |
3004165 | Urine Volume: | 3167-4 |
3004166 | Creatinine Concentration, 24 Hour Urine | 20624-3 |
3004793 | Leukotriene E4, 24 Hour Urine | 101115-4 |
Aliases
- Cysteinyl Leukotriene
- LTE4
- Mastocytosis
- Systemic mast Cell Activation
Mayo Clinic Laboratories