Search our extensive Laboratory Test Directory to find test codes, ordering recommendations, specimen stability information, Test Fact Sheets, and more.
Recommendations when to order or not order the test. May include related or preferred tests.
Aids in the initial diagnosis of suspected mast cell activation disorders. A 24-hour urine collection of 300 mL or greater is required. If submitting a random urine or 24-hour collection with a total volume of less than 300 mL, refer to Leukotriene E4, Random Urine (3002351).
New York DOH Approval Status
Indicates whether a test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
Patients taking 5-lipoxygenase inhibitor zileuton (Zyflo) may have decreased concentrations of leukotriene E4 (LTE4). If possible, discontinue 48 hours prior to collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
24-hour urine. Refrigerate during collection.
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
From a well-mixed 24-hour collection transfer 5 mL urine to ARUP standard transport tubes (Min: 2 mL). Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
Frozen. Also acceptable: Refrigerated
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
RemarksAdditional specimen collection, transport, or test submission information.
Collection duration and urine volume must be provided for testing. Total collection volume must be greater than 300 mL.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
Ambient: 24 hours; Refrigerated: 1 week; Frozen: 28 days
Methodology
Process(es) used to perform the test.
Quantitative Colorimetry/Liquid Chromatography-Tandem Mass Spectrometry
Performed
Days of the week the test is performed.
Varies
Reported
Expected turnaround time for a result, beginning when ARUP has received the specimen.
6-11 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
By Report
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
Compliance Category
Performed by non-ARUP Laboratory
Note
Additional information related to the test.
Hotline History
History of test changes published on ARUP Hotlines for the last two years
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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